@article{Afham_Teruna_Hendra_2022, title={IAI SPECIAL EDITION: The potential of Mimosa pudica L as an α- glucosidase inhibitor and antioxidant agent }, volume={22}, url={https://pharmacyeducation.fip.org/pharmacyeducation/article/view/1579}, DOI={10.46542/pe.2022.222.14}, abstractNote={<p><strong>Background:</strong> The <em>putri malu</em> plant (<em>Mimosa pudica</em> L.) is a South American and Central American native widely distributed throughout Indonesia. Indonesians utilise this plant as a herbal treatment to treat various ailments, including insomnia, acute eye inflammation, stone pee, fever, worms, bronchitis, and herpes.   </p> <p><strong>Objectives:</strong> This plant was studied for its antioxidant and α-glucosidase inhibitory activities using <em>n</em>-hexane, dichloromethane, ethyl acetate, and water extracts.   <strong> </strong></p> <p><strong>Method:</strong> The aerial part of the plant was extracted with methanol and partitioned with <em>n</em>-hexane, dichloromethane (DCM), and ethyl acetate to obtain <em>n</em>-hexane (EHMP) dichloromethane (EDMP), ethyl acetate (EEMP), and water (EAMP) extracts. All extracts were analysed for their α-glucosidase inhibitor and antioxidants with the free radical <em>scavenging activity</em> method using DPPH.    </p> <p><strong>Results:</strong> EAMP showed antidiabetic activity with inhibition of 69.9% at a concentration of 500 ppm, and other extracts showed no α-glucosidase inhibition activity. For antioxidant activity, EDMP, EEMP, and EAMP showed relatively high activity with IC<sub>50</sub> consecutively 77.4 ppm, 26.9 ppm, and 81.4 ppm, while EHMP had a reasonably low activity with IC50 635.6 ppm.   </p> <p><strong>Conclusion:</strong> The study results showed that <em>M. pudica</em> has considerable potential as a source of antidiabetics and natural antioxidants, so it is necessary to isolate secondary metabolites from the species.</p>}, number={2}, journal={Pharmacy Education}, author={Afham, Muhamad and Teruna, Hilwan Yuda and Hendra, Rudi}, year={2022}, month={Mar.}, pages={p. 1–4} }