@article{Teruna_Hendra_Almurdani_2022, title={IAI SPECIAL EDITION: α-Glucosidase inhibitory activities of Loranthus ferrugineus and Peperomia pellucida extracts}, volume={22}, url={https://pharmacyeducation.fip.org/pharmacyeducation/article/view/1580}, DOI={10.46542/pe.2022.222.58}, abstractNote={<p><strong>Introduction</strong>: The usage of traditional medicines in Indonesia has recently increased following the rise in regional COVID-19 cases. They were used to alleviate the symptoms of patients with pre-existing condition such as heart diseases, diabetes mellitus, and inflammation. They were also used to boost peoples immune system. <em>Loranthus ferrugineus</em> (Loranthaceae) and <em>Peperomia pellucida</em> (Piperaceae) were two medicinal plants used as anti-diabetes drugs.   </p> <p><strong>Aim</strong>: This study aimed to measure the anti-diabetic activity of extracts of <em>L. ferrugineus</em> branches and the aerial parts of <em>P. pellucida</em>.    </p> <p><strong>Method</strong>: Dried branches of <em>L. ferrugineus</em> were macerated using <em>n</em>-hexane, ethyl acetate, and methanol, respectively. Fresh aerial parts of <em>P. pellucida</em> were macerated with methanol and reduced the volume <em>in vacuo.</em> The extract was fractionated with <em>n</em>-hexane and ethyl acetate. These extracts and its fractions were dried and tested <em>in vitro </em>with <em>α</em>-glucosidase.    </p> <p><strong>Results</strong>: α-Glucosidase inhibitory activities of ethyl acetate and methanol of <em>L. ferrugineus</em> were 89.21% and 92.98% at 500 ppm. However, there was no significant activity detected for the <em>n</em>-hexane extract.  α-Glucosidase inhibitory activities of methanol extract, and its <em>n</em>-hexane and ethyl acetate fractions of <em>P. pellucida</em> were 8.26%, 0.83% and 28.19% at 500 ppm.    </p> <p><strong>Conclusion:</strong> The methanol extract of <em>L. ferrugineus</em> and the ethyl acetate extract of <em>L. ferrugineus</em> are considered to have potential to be developed further as therapeutics.</p>}, number={2}, journal={Pharmacy Education}, author={Teruna, Hilwan Yuda and Hendra, Rudi and Almurdani, Muhammad}, year={2022}, month={Mar.}, pages={p. 5–8} }