RESEARCH ARTICLE: Emergency compounding of COVID-19 medicines: A readiness programme to up-skill pharmacy graduates in Namibia

Authors

DOI:

https://doi.org/10.46542/pe.2020.202.117123

Keywords:

COVID-19, Compounding, Emergence, Medicines, Pharmacy Education

Abstract

Background: The COVID-19 pandemic has exacerbated inequitable access to medicines in sub-Saharan Africa, mainly due to limited capabilities for local manufacture.

Aim: To describe priority medicine lists and critical skill sets required for an emergency compounding of COVID-19 medicines training programme.

Methods: An evaluation of the COVID-19 emergency compounding readiness programme for the University of Namibia pharmacy graduates. The main outcomes were enhanced skill sets in compounding, quality control, and regulation of priority COVID-19 medicines. Data on outcomes were thematically analysed.

Results: Fifty- eight pharmacy graduates demonstrated competence in emergency compounding, quality control, regulation, and provision of therapeutic information of COVID-19 medicines. A priority list and a skills set for emergency compounding of COVID-19 medicines were developed.

Conclusions: The upskilling of pharmacy graduates on emergency compounding of COVID-19 medicines has the potential to address inequalities in the rapid response and control of epidemics.

Author Biographies

Daniel Mavu, University of Namibia, Namibia

Department of Pharmaceutics, School of Pharmacy, Faculty of Health Sciences

Mwangana Mubita, University of Namibia, Namibia

Department of Pharmacy Practice and Policy, School of Pharmacy, Faculty of Health Sciences, 

Qamar Niaz, University of Namibia, Namibia

Department of Pharmacy Practice and Policy, School of Pharmacy, Faculty of Health Sciences

Monde Lusepani, University of Namibia, Namibia

Department of Pharmaceutical Chemistry and Phytochemistry, School of Pharmacy, Faculty of Health Sciences

Seth Nowaseb, University of Namibia, Namibia

Department of Pharmaceutical Chemistry and Phytochemistry, School of Pharmacy, Faculty of Health Sciences

Tonata Enkara, University of Namibia, Namibia

Department of Pharmaceutics, School of Pharmacy, Faculty of Health Sciences

Aiases Philomiene, University of Namibia, Namibia

Department of Pharmaceutics, School of Pharmacy, Faculty of Health Sciences

 

Riana Pick, University of Namibia, Namibia

Department of Pharmaceutics, School of Pharmacy, Faculty of Health Sciences

Dan Kibuule, University of Namibia, Namibia

Department of Pharmacy Practice and Policy, School of Pharmacy, Faculty of Health Sciences

References

Amimo, F., Lambert, B., & Magit, A. (2020). What does the COVID-19 pandemic mean for HIV, tuberculosis, and malaria control? Tropical Medicine and Health, 48(32). https://doi.org/10.1186/s41182-020-00219-6

Aruru, M., Truong, H. A., & Clark, S. (2020). Pharmacy Emergency Preparedness and Response (PEPR) framework for expanding pharmacy professionals’ roles and contributions to emergency preparedness and response during the COVID-19 pandemic and beyond. Research in Social & Administrative Pharmacy, 17(1), 1967–1977. https://doi.org/10.1016/j.sapharm.2020.04.002

Da Costa, F.A., Lee, V., Leite, S.N., Murillo, M.D., Menge, T., & Antoniou, S. (2020). Pharmacists reinventing their roles to effectively respond to COVID-19: A global report from the international pharmacists for anticoagulation care taskforce (iPACT). Journal of Pharmaceutical Policy and Practice, 13(12). https://doi.org/10.1186/s40545-020-00216-4

Ellis, F. (2002). Paracetamol - a curriculum resource. Royal Society of Chemistry, London

Gilbert, M., Pullano, G., Pinotti, F., Valdano, E., Poletto, C., Boëlle, P.Y., D’Ortenzio, E., Yazdanpanah, Y., Eholie, S.P., Altmann, M., Gutierrez, B., Kraemer, M.U.G., & Colizza, V. (2020). Preparedness and vulnerability of African countries against importations of COVID-19: a modelling study. The Lancet, 395, 871-877. https://doi.org/10.1016/S0140-6736(20)30411-6

Govindan, K., Mina, H., & Alavi, B. (2020). A decision support system for demand management in healthcare supply chains considering the epidemic outbreaks: A case study of coronavirus disease 2019 (COVID-19). Transportation Research Part E: Logistics and Transportation Review, 1019672. https://doi.org/10.1016/j.tre.2020.101967

Guan, D., Wang, D., Hallegatte, S., Davis, S.J., Huo, J., Li, S., Bai, Y., Lei, T., Xue, Q., Coffman, D.M., Cheng, D., Chen, P., Liang, X., Xu, B., Lu, X., Wang, S., Hubacek, K., & Gong, P. (2020). Global supply-chain effects of COVID-19 control measures. Nature Human Behaviour, 4, 577-587. https://doi.org/10.1038/s41562-020-0896-8

Jacobsen, K.H. (2020). Will COVID-19 generate global preparedness? The Lancet, 395, 1013-1014. https://doi.org/10.1016/S0140-6736(20)30559-6

Kibuule, D., Nambahu, L., Sefah, I.A., Kurdi, A., Phuong, T.N.T., Kwon, H.-Y., & Godman, B. (2020). Activities in Namibia to limit the impact of COVID-19 versus Europe and Iran and the implications for the future. Federation of Infection Societies/Healthcare Infection Society International. https://doi.org/10.1155/2010/706872

Lone, S.A., & Ahmad, A. (2020). COVID-19 pandemic–an African perspective. Emerging Microbes and Infections, 9(1), 1300-1308. https://doi.org/10.1080/22221751.2020.1775132

Lumu, I. (2020). COVID-19 Response in Sub-Saharan Africa: Lessons from Uganda. Disaster Medicine and Public Health Preparedness, 14(3), 46-48. https://doi.org/10.1017/dmp.2020.248

Ogunleye, O.O., Basu, D., Mueller, D., Sneddon, J., Seaton, R.A., Yinka-Ogunleye, A.F., Wamboga, J., Miljković, N., Mwita, J.C., Rwegerera, G.M., Massele, A., Patrick, O., Niba, L.L., Nsaikila, M., Rashed, W.M., Hussein, M.A., Hegazy, R., Amu, A.A., Boahen-Boaten, B.B., et al. (2020). Response to the Novel Corona Virus (COVID-19) Pandemic Across Africa: Successes, Challenges, and Implications for the Future. Frontiers in Pharmacology, 11, 1–36. https://doi.org/10.3389/fphar.2020.01205

Paumgartten, F.J.R., & Oliveira, A.C.A.X.D. (2020). Off label, compassionate and irrational use of medicines in Covid-19 pandemic, health consequences and ethical issues. Ciencia & saude coletiva, 25, 3413-3419. https://doi.org/10.1590/1413-81232020259.16792020

Ramia, E., Salameh, P., Btaiche, I.F., & Saad, A.H. (2016). Mapping and assessment of personal and professional development skills in a pharmacy curriculum. BMC Medical Education, 16(1), 19. https://doi.org/10.1186/s12909-016-0533-4

Rennie, T., Kibuule, D., Haakuria, V., & Adorka, M. (2014). Four years on in Namibia: What of the new pharmacy programme. International Pharmacy Journal, 32(1), 58-60

Schellack, N., Coetzee, M., Schellack, G., Gijzelaar, M., Hassim, Z., Milne, M., Bronkhorst, E., Padayachee, N., Singh, N., Kolman, S., & Gray, A.L. (2020). COVID-19: Guidelines for pharmacists in South Africa. Southern African Journal of Infectious Diseases, 35(1). https://doi.org/10.4102/sajid.v35i1.206

Schneider, M., & Ho Tu Nam, N. (2020). Africa and counterfeit pharmaceuticals in the times of COVID-19. Journal of Intellectual Property Law & Practice, 15(6), 417-418. https://doi.org/10.1093/jiplp/jpaa073

Walters, D.B., Chawla, I.D., & Rogers, D.W. (1968). Determination of Alcohol Content in Beverages by Phase Titration. Journal of Agricultural and Food Chemistry, 16(2), 259–261. https://doi.org/10.1021/jf60156a009

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Published

11-01-2021

How to Cite

Mavu, D. ., Mubita, M., Niaz, Q., Lusepani, M., Nowaseb, S. ., Enkara, T. ., Philomiene, A., Pick, R., & Kibuule, D. (2021). RESEARCH ARTICLE: Emergency compounding of COVID-19 medicines: A readiness programme to up-skill pharmacy graduates in Namibia. Pharmacy Education, 20(2), p. 117 – 123. https://doi.org/10.46542/pe.2020.202.117123

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Section

COVID-19 Research Paper