REVIEW: Clinical pharmacists' scope of knowledge for medication therapy management in chronic kidney disease patients

Authors

DOI:

https://doi.org/10.46542/pe.2021.211.781788

Keywords:

Chronic kidney disease, Medication therapy management, Medication therapy review, Quality of life

Abstract

Medication therapy management (MTM) was first implemented and introduced for chronically ill patients and those taking multiple prescription drugs. The MTM has five steps, namely medication therapy review (MTR), personal medication record (PMR), medication-related action plan (MAP), intervention or referral, and finally, documentation. After receiving MTM services, patients will gain knowledge on medicines, which may decrease non-adherence to treatment and increase its efficacy. Studies have shown the positive impact of MTM on geriatric, pediatric, and chronically ill patients and those on polypharmacy. MTM services may improve medication adherence, decrease healthcare costs, and improve the quality of life (QoL) of patients with chronic kidney disease (CKD) by addressing various issues like anaemia, metabolic acidosis, protein management, fluid management, electrolyte management, dosage adjustment based on eGFR, vaccination, and medication-related problems and intervening with the education about the disease, drugs, and lifestyle modifications.

Author Biographies

Sirimalla Shivaprasad, Nitte Deemed to be University, Deralakatte, Mangaluru, Karnataka, India

Department of Pharmacy Practice, NGSM Institute of Pharmaceutical Sciences

Uday Venkat Mateti, Nitte Deemed to be University, Deralakatte, Mangaluru, Karnataka, India

Department of Pharmacy Practice, NGSM Institute of Pharmaceutical Sciences

Pradeep Shenoy, Nitte Deemed to be University, Deralakatte, Mangaluru, Karnataka, India

Department of Nephrology, K.S. Hegde Medical Academy

Chakrakodi Shashidhara Shastry, Nitte Deemed to be University, Deralakatte, Mangaluru, Karnataka, India

Department of Pharmacy Practice, NGSM Institute of Pharmaceutical Sciences

Sreedhar Dharmagadda, Manipal Academy of Higher Education, Manipal, Karnataka, India

Department of Pharmacy Management, Manipal College of Pharmaceutical Sciences

References

Acute care testing org your scientific knowledge site. (2007). Ionized calcium (online). Available at: https://acutecaretesting.org/-/media/acutecaretesting/files/pdf/ionized-calcium.pdf

Al Raiisi F, Stewart D, Fernandez-Llimos F, Salgado TM, Mohamed MF, Cunningham S. (2019). Clinical pharmacy practice in the care of Chronic Kidney Disease patients: a systematic review. Int J Clin Pharm. 41(3): 630-666. https://doi.org/10.1007/s11096-019-00816-4

American Kidney Fund. (2021). Fluid and stages of kidney disease (online). Available at: https://kitchen.kidneyfund.org/general-nutrients/fluid/#:~:text=When%20you%20have%20kidney%20disease,kidneys%20hydrated%20and%20working%20well

Couser, W. G., Remuzzi, G., Mendis, S., & Tonelli, M. (2011). The contribution of chronic kidney disease to the global burden of major non-communicable diseases. Kidney international, 80(12), 1258–1270. https://doi.org/10.1038/ki.2011.368

GBD Chronic Kidney Disease Collaboration (2020). Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet, 395(10225), 709–733. https://doi.org/10.1016/S0140-6736(19)32977-0

Hassan, Y., Al-Ramahi, R. J., Aziz, N. A., &Ghazali, R. (2009). Impact of a renal drug dosing service on dose adjustment in hospitalized patients with chronic kidney disease. The Annals of pharmacotherapy, 43(10), 1598–1605. https://doi.org/10.1345/aph.1M187

Indian journal of nephrology. (2016). Guidelines for vaccination in patients with chronic kidney disease (online). Available at: http://isn-india.org/images/Indian-Society-of-Nephrology-Guidelines-for-vaccination-of-Chronic-Kidney-Disease.pdf

James, P. A., Oparil, S., Carter, B. L., Cushman, W. C., Dennison-Himmelfarb, C., Handler, J., et al. (2014). 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA, 311(5), 507–520. https://doi.org/10.1001/jama.2013.284427

Ko, G. J., Obi, Y., Tortorici, A. R., &Kalantar-Zadeh, K. (2017). Dietary protein intake and chronic kidney disease. Current opinion in clinical nutrition and metabolic care, 20(1), 77–85. https://doi.org/10.1097/MCO.0000000000000342

Levey, A. S., Stevens, L. A., Schmid, C. H., Zhang, Y. L., Castro, A. F., 3rd, Feldman, H. I., Kusek, J. W., et al. (2009). A new equation to estimate glomerular filtration rate. Annals of internal medicine, 150(9), 604–612. https://doi.org/10.7326/0003-4819-150-9-200905050-00006

Lin, H. W., Lin, C. H., Chang, C. K., Chou, C. Y., Yu, I. W., Lin, C. C., et al. (2018). Economic outcomes of pharmacist-physician medication therapy management for polypharmacy elderly: A prospective, randomized, controlled trial. Journal of the Formosan Medical Association, 117(3), 235–243. https://doi.org/10.1016/j.jfma.2017.04.017

Marriott, J., Cockwell, P., Stringer, S. (2012). Chronic kidney disease and end-stage renal disease. In: Walker. R. & Whittlesea. C. (Eds), Clinical pharmacy and therapeutics (pp.272-294). China: Churchill livingstone Elsevier

Mason N. A. (2011). Polypharmacy and medication-related complications in the chronic kidney disease patient. Current opinion in nephrology and hypertension, 20(5), 492–497. https://doi.org/10.1097/MNH.0b013e328349c261

Mason, D.L., Assimon, M. M. (2013). Renal disorders. In: B. K. Alldredge& R. L. Corelli (Eds.), Applied therapeutics the clinical use of drugs (pp. 764-796). Philadelphia: Wolters Kluwer| Lippincott Williams and Wilkins

Medication Therapy Management in Pharmacy Practice. (2008). Core Elements of an MTM Service Model (online). Available at: https://pharmacistsprovidecare.com/sites/default/files/core_elements_of_an_mtm_practice.pdf

MEDSAFE New Zealand Medicines and Medical Devices Safety Authority. (2015). Nitrofurantoin - Not Suitable in Renal Impairment (online). Available at: https://www.medsafe.govt.nz/profs/PUArticles/December2015/Nitrofurantoin.htm

Michigan Medicine University of Michigan. (2019). Management of Chronic Kidney Disease. Available at: http://www.med.umich.edu/1info/FHP/practiceguides/kidney/CKD.pdf

Mimura, I., Tanaka, T., Nangaku, M. (2015). How the Target Hemoglobin of Renal Anemia Should be?. Nephron clinical practice, 131: 202-209. https://doi.org/10.1159/000440849

National Institute for Health and Care Excellence. (2020) Hyperphosphatemia in chronic kidney disease overview (online). Available at: http://pathways.nice.org.uk/pathways/hyperphosphataemia-in-chronic-kidney-disease

National institute of diabetes and digestive and kidney diseases. (2010) Phosphorus Tips for People with Chronic Kidney Disease (CKD) (online). Available at: https://www.niddk.nih.gov/-/media/Files/Health-Information/Health-Professionals/Kidney-Disease/PhosphorusTipsforPeopleCKD_EN.pdf

National institute of diabetes and digestive and kidney diseases. (2010). Protein Tips for People with Chronic Kidney Disease (CKD) (online). Available at: https://www.niddk.nih.gov/-/media/Files/Health-Information/Health-Professionals/Kidney-Disease/ProteinTipsforPeopleCKD_EN.pdf

National institute of diabetes and digestive and kidney diseases. (2011). Potassium Tips for People with Chronic Kidney Disease (CKD) (online). Available at: https://www.niddk.nih.gov/-/media/Files/Health-Information/Health-Professionals/Kidney-Disease/PotassiumTipsforPeopleCKD_EN.pdf

National Kidney Foundation. (2014) Nutrition and Chronic Kidney Disease (STAGE 1-4) (online). Available at: https://www.kidney.org/sites/default/files/11-50-0114_docsnutrikidfail_stage1-4.pdf

Ohnishi J, Miyake A, Kuwatsuka K, Onoue Y, Lee M, Koyama T, et al. (2011). Effect of pharmacist management on serum hemoglobin levels with renal anemia in hemodialysis outpatients. Biol Pharm Bull. 34(10): 1609-12. https://doi.org/10.1248/bpb.34.1609

Onder, A. M., Espinoza, V., Berho, M. E., Chandar, J., Zilleruelo, G., & Abitbol, C. (2006). Acute renal failure due to phenazopyridine (Pyridium) overdose: case report and review of the literature. Pediatric nephrology (Berlin, Germany), 21(11), 1760–1764. https://doi.org/10.1007/s00467-006-0196-1

Public law 108–173. (2003). Medicare prescription drug improvement and modernization act of 2003 (online). Available at: https://www.congress.gov/108/plaws/publ173/PLAW-108publ173.pdf

Rogers, J., Leung, M., Beaulieu, M., Levin, A., Burnett, S., & Zienkiewicz, A. (2011). Evaluation of anemia management by algorithms in patients with chronic kidney disease who are not receiving dialysis. The Canadian journal of hospital pharmacy, 64(2), 141–146. https://doi.org/10.4212/cjhp.v64i2.998

Singh, A. K., Farag, Y. M., Mittal, B. V., Subramanian, K. K., Reddy, S. R., Acharya, V. N., et al. (2013). Epidemiology and risk factors of chronic kidney disease in India - results from the SEEK (Screening and Early Evaluation of Kidney Disease) study. BMC nephrology, 14, 114. https://doi.org/10.1186/1471-2369-14-114

Stemer, G., & Lemmens-Gruber, R. (2011). Clinical pharmacy activities in chronic kidney disease and end-stage renal disease patients: a systematic literature review. BMC nephrology, 12, 35. https://doi.org/10.1186/1471-2369-12-35

Wojcicki J. M. (2013). Hyperphosphatemia is associated with anemia in adults without chronic kidney disease: results from the National Health and Nutrition Examination Survey (NHANES): 2005-2010. BMC nephrology, 14, 178. https://doi.org/10.1186/1471-2369-14-178

Downloads

Published

02-12-2021

How to Cite

Shivaprasad, S. ., Mateti, U. V. ., Shenoy, P., Shastry, C. S. ., & Dharmagadda, S. . (2021). REVIEW: Clinical pharmacists’ scope of knowledge for medication therapy management in chronic kidney disease patients . Pharmacy Education, 21, p. 781–788. https://doi.org/10.46542/pe.2021.211.781788

Issue

Section

Review