IAI CONFERENCE: The effect of ethanol extract from Portulaca oleracea on inhibiting total cholesterol on animal subjects
DOI:
https://doi.org/10.46542/pe.2021.212.2226Keywords:
Anti hypercholesterol, Krokot, PurslaneAbstract
Introduction: Hypercholesterolemia occurs when cholesterol levels in the blood increases. Traditionally, krokot (purslane, portulaca oleracea) is used to treat cardiovascular disease.
Aim: This research evaluated the effect of purslane extract to inhibit increasing of cholesterol levels.
Methods: The ethanol extract dosage of purslane was 27.5, 55, and 110 mg/kg body weight (bw) and simvastatin 1.8 mg/kg bw were used as comparisons. The anti-hyper cholesterol effect test was done by feeding a high cholesterol diet and drinks containing 0.01% propylthiouracil. The test parameters were body weight and total cholesterol levels on days 0, 7, 14, and 21.
Results: The results showed that the extract was able to prevent the increase in body weight compared to the control group (p<0.05) and that it could inhibit the increase of total cholesterol levels at day 14 and 21 compared to control group (p<0.05) and equivalent to simvastatin (p>0.05).
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