IAI CONFERENCE: The evaluation of compounding prescription and its availability of a licensed product for children at a private hospital in Yogyakarta, Indonesia
DOI:
https://doi.org/10.46542/pe.2021.212.9397Keywords:
Compounding, Extemporaneous preparation, Licensed drug formula, Prescribing profileAbstract
Introduction: The availability of licensed drug formulas for paediatric patients is still limited, so compounded drugs still exist, especially in the form of divided medicinal powder.
Aim: This study aimed to determine the profile of divided medicinal powder prescription and its availability in licensed drug formula for paediatric patients.
Methods: This research was a cross-sectional study. Prescriptions containing order to compound divided medicinal powder at a ublic Hospital in Yogyakarta Special Region from January to March 2019, were collected and analysed descriptively.
Results: The total collected prescriptions were 152. The total of active substances given to paediatric patients was 38. The most prescribed drug in the hospital was Triamcinolone. There are 34 active substances already available in licensed drug formulas for paediatric patients, so it is better not to be compounded. However, four active substances are not available as licensed product in the drug information handbook in Indonesia, so, it is reasonable to compound to provide a suitable medication (dose and dosage form) for paediatric patients.
References
Gudeman, J., Jozwiakowski, M., Chollet, J., & Randell, M. (2013). Potential risks of pharmacy compounding. In Drugs in R and D, 13 (1), pp. 1–8. https://doi.org/10.1007/s40268-013-0005-9
Jackson, M., & Lowey, A. (2010). Handbook of Extemporaneous Preparation A Guide to Pharmaceutical Compounding. Pharmaceutical Press
Kristina, S., Wiedyaningsih, C., Widyakusuma, N.N., & Aditama, H. (2017). Extemporaneous compounding practice by pharmacists: a systematic review. International Journal of Pharmacy and Pharmaceutical Sciences, 9(2), 42–46. https://doi.org/10.22159/ijpps.2017v9i2.15681
Kristina, S.A., Wiedyaningsih, C., Widyakusuma, N.N., & Aditama, H. (2018). Profile and determinants of compounding services among pharmacists in Indonesia. Asian Journal of Pharmaceutics, 12(3), 966–970
Piliarta, I.N.G., Dewa, A.S., & Noviyani, R. (2012). Kajian Kelengkapan Resep Pediatri Rawat Jalan yang Berpotensi Menimbulkan Medication Error di Rumah Sakit Swasta di Kabupaten Gianyar. Jurnal Farmasi Udayana, 1(1)
Rochjana, A., Jufri, M., & Andrajati, R. (2019). Masalah farmasetika dan interaksi obat pada resep racikan pasien pediatri: studi retrospektif pada salah satu rumah sakit di Kabupaten Bogor. Journal.Unpad.Ac.Id, 8(1), 42–48. https://doi.org/10.15416/ijcp.2019.8.1.42
Setyani, W., & Putri, D.C.A. (2019). Resep Dan Peracikan Obat. Sanata Dharma University Press
Virginia, D.M. (2014). PERESEPAN SEDIAAN RACIKAN PADA PASIEN ANAK DI BANGSAL RAWAT INAP. Jurnal Penelitian, 18(1). Available at: https://e-journal.usd.ac.id/index.php/JP/article/view/807
Widyaswari, R., & Wiedyaningsih, C. (2012). Evaluasi Profil Peresepan Obat Racikan dan Ketersediaan Formula Obat untuk Anak di Puskermas Provinsi DIY. Majalah Farmaseutik, 8(3), 227–234. Available at: https://journal.ugm.ac.id/majalahfarmaseutik/article/view/24079/15756
Wiedyaningsih, C., Widyaswari, R., Hasani, M., & Dhani, W. (2012). Compounding Prescription Patterns: Factors Influencing the Physicians to Prescribe Compounded Medicines for Paediatric Outpatients. Research in Social and Administrative Pharmacy, 8(6), e29. https://doi.org/10.1016/J.SAPHARM.2012.08.067
Wiedyaningsih, Chairun, & O. (2005). Investigation on drug dosage form : analysis of prescriptions available in pharmacy in kotamadya Yogyakarta. Indonesian Journal of Pharmacy, 0(0), 201–207. https://doi.org/10.14499/INDONESIANJPHARM0ISS0PP201-207
