IAI CONFERENCE: Microencapsulation of Jeringau Rhizome essential oils (Acorus calamus L.) using β-Cyclodextrin

Authors

  • Ledianasari Sekolah Tinggi Farmasi Indonesia, Bandung, West Java, Indonesia
  • Deby Tristiyanti Sekolah Tinggi Farmasi Indonesia, Bandung, West Java, Indonesia
  • Elva Maulydha Tanjung Sekolah Tinggi Farmasi Indonesia, Bandung, West Java, Indonesia
  • Lovelyta Barani Sekolah Tinggi Farmasi Indonesia, Bandung, West Java, Indonesia

DOI:

https://doi.org/10.46542/pe.2021.212.189194

Keywords:

β-cyclodextrin, Essential oils, Freeze-drying jeringau rhizome, Microencapsulation

Abstract

Background: The way to improve the stability of jeringau rhizome essential oils is microencapsulation using β-cyclodextrin.    

Aim: To determine the efficiency of coating the jeringau rhizome essential oil with β-cyclodextrin and examine its thermostability.   

Method: The microencapsulation method used was freeze-drying with a ratio of 1:20 and 1:30.    

Results: The microcapsule efficiency at the ratio of 1:20 and 1:30 was 81.67% and 60.70%, respectively. The thermostability test results showed that the degradation constant of 1:20 microcapsule at 50oC and ambient temperature was 0.0054 and 0.0029, respectively, with a half-life of 128.33 hours and 238.97 hours. Meanwhile, the degradation constant of 1:30 microcapsule was 0.0182 and 0.0080, with a half-life of 38.07 hours and 86.63 hours.   

Conclusion: The highest efficiency is in the ratio of 1:20 with a percentage of 81.67%. In the thermostability test, the 1:20 microcapsule was better protected and had a longer half-life than the 1:30 microcapsule.

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Published

28-07-2021

How to Cite

Ledianasari, Tristiyanti, D. ., Tanjung, E. M. ., & Barani, L. . (2021). IAI CONFERENCE: Microencapsulation of Jeringau Rhizome essential oils (Acorus calamus L.) using β-Cyclodextrin. Pharmacy Education, 21(2), p. 189–194. https://doi.org/10.46542/pe.2021.212.189194

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Conference Proceedings