IAI SPECIAL EDITION: Antioxidant activity assay of Agarwood leaf extract cream (Aquilaria malaccensis L.) using free radical scavenging method

Authors

  • Abdul Rahman Wahid University of Muhammadiyah Mataram, Mataram, Indonesia
  • Yuli Fitriana University of Muhammadiyah Mataram, Mataram, Indonesia
  • Alvi Kusuma Wardani University of Muhammadiyah Mataram, Mataram, Indonesia
  • Lisa Apriana Heru Listari University of Muhammadiyah Mataram, Mataram, Indonesia

DOI:

https://doi.org/10.46542/pe.2022.222.2429

Keywords:

Antioxidant Activity, DPPH, Agarwood leaf (A. malaccensis L.), Extract, Cream

Abstract

Background: Agarwood leaves (A. malaccensis L.) are the part of the plant that is rich in antioxidants and contain phytochemicals, namely: alkaloids, flavonoids, terpenoids, steroids, and saponins.    

Objective: This research aimed to determine the antioxidant activity of cream-containing Agarwood leaf extract using the DPPH (1,1-diphenyl-2-picrylhydrazyl) free radical.

Method: The sample was extracted by 70% ethanol and formulated at concentrations of 1% weight/volume (w/v), 3% w/v, and 5% w/v. Physical characteristics and antioxidant activity were evaluated.   

Results: The results showed that the agarwood leaf extract cream in all concentrations fulfilled all the requirements related to physical characteristics of good topical preparations, including organoleptic, homogeneity, pH, spreadability, and adhesion. The IC50 values of the agarwood leaf extract cream at the concentrations of 1% w/v, 3% w/v, and 5% w/v were 68.371, 62.602, and 57.756 ppm, respectively.      

Conclusion: This research concluded that agarwood leaf extract cream has high antioxidant or free radical scavenging properties (50 ppm-100 ppm).

Author Biographies

Abdul Rahman Wahid, University of Muhammadiyah Mataram, Mataram, Indonesia

Faculty of Health Sciences

Yuli Fitriana, University of Muhammadiyah Mataram, Mataram, Indonesia

Faculty of Health Sciences

Alvi Kusuma Wardani, University of Muhammadiyah Mataram, Mataram, Indonesia

Faculty of Health Sciences

Lisa Apriana Heru Listari, University of Muhammadiyah Mataram, Mataram, Indonesia

Faculty of Health Sciences

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Published

2022-03-31

How to Cite

Wahid, A. R., Fitriana, Y., Wardani, A. K. ., & Listari, L. A. H. . (2022). IAI SPECIAL EDITION: Antioxidant activity assay of Agarwood leaf extract cream (Aquilaria malaccensis L.) using free radical scavenging method. Pharmacy Education, 22(2), p. 24–29. https://doi.org/10.46542/pe.2022.222.2429

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Special Edition