IAI SPECIAL EDITION: Formulation and effectivity testing of pining fruit extract gel (Hornstedtia alliacea) for healing burns

Authors

  • Firman Gustaman STIKes Bakti Tunas Husada, Tasikmalaya, Indonesia
  • Fajar Setiawan STIKes Bakti Tunas Husada, Tasikmalaya, Indonesia
  • Nida Nur Fadhilah STIKes Bakti Tunas Husada, Tasikmalaya, Indonesia
  • Keni Idacahyati STIKes Bakti Tunas Husada, Tasikmalaya, Indonesia
  • Winda Trisna Wulandari STIKes Bakti Tunas Husada, Tasikmalaya, Indonesia
  • Indra Indra STIKes Bakti Tunas Husada, Tasikmalaya, Indonesia

DOI:

https://doi.org/10.46542/pe.2022.222.109112

Keywords:

Burn, Gel, Hornstedtia alliacea, Pining fruit

Abstract

Background: Pining fruit is a traditional medicinal plant employed to treat burns for its content of active natural ingredients such as flavonoids, tannins, and saponins acting as antioxidants and anti-inflammatory.    

Objective: The objective of this study was to formulate the best formula for gel preparations and test the effectiveness of pining fruit extract gel preparations for healing burns.   

Methods: Evaluation tests of the gel preparations included organoleptic, homogeneity, pH, spreadability, and viscosity tests. The gel effectiveness test was conducted in five treatment groups for 14 days. The data were analysed statistically using the one-way ANOVA method followed by the LSD (Least Significant Different) test.    

Results: The physical evaluation of pining fruit gel preparations, i.e. organoleptic, homogeneity, pH, dispersion, and viscosity tests on all three formulas (F1, F2, and F3), met the requirements. The results of the one-way ANOVA analysis revealed a significant difference in the experimental group with a score of 0.022 (p < 0.05). Hence, the most effective formula for curing burns was F3, with a 1.5% extract concentration and a healing percentage of 19.175%.

Author Biographies

Firman Gustaman, STIKes Bakti Tunas Husada, Tasikmalaya, Indonesia

Pharmacist Professional Education Study Program

Fajar Setiawan, STIKes Bakti Tunas Husada, Tasikmalaya, Indonesia

Pharmacist Professional Education Study Program

Nida Nur Fadhilah, STIKes Bakti Tunas Husada, Tasikmalaya, Indonesia

Pharmacist Professional Education Study Program

Keni Idacahyati, STIKes Bakti Tunas Husada, Tasikmalaya, Indonesia

Pharmacist Professional Education Study Program

Winda Trisna Wulandari, STIKes Bakti Tunas Husada, Tasikmalaya, Indonesia

Pharmacist Professional Education Study Program

Indra Indra, STIKes Bakti Tunas Husada, Tasikmalaya, Indonesia

Pharmacist Professional Education Study Program

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Published

2022-03-31

How to Cite

Gustaman, F. ., Setiawan, F. ., Fadhilah, N. N. ., Idacahyati, K. ., Wulandari, W. T. ., & Indra, I. . (2022). IAI SPECIAL EDITION: Formulation and effectivity testing of pining fruit extract gel (Hornstedtia alliacea) for healing burns. Pharmacy Education, 22(2), p. 109–112. https://doi.org/10.46542/pe.2022.222.109112

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Section

Special Edition