IAI SPECIAL EDITION: Formulation and effectivity testing of pining fruit extract gel (Hornstedtia alliacea) for healing burns
DOI:
https://doi.org/10.46542/pe.2022.222.109112Keywords:
Burn, Gel, Hornstedtia alliacea, Pining fruitAbstract
Background: Pining fruit is a traditional medicinal plant employed to treat burns for its content of active natural ingredients such as flavonoids, tannins, and saponins acting as antioxidants and anti-inflammatory.
Objective: The objective of this study was to formulate the best formula for gel preparations and test the effectiveness of pining fruit extract gel preparations for healing burns.
Methods: Evaluation tests of the gel preparations included organoleptic, homogeneity, pH, spreadability, and viscosity tests. The gel effectiveness test was conducted in five treatment groups for 14 days. The data were analysed statistically using the one-way ANOVA method followed by the LSD (Least Significant Different) test.
Results: The physical evaluation of pining fruit gel preparations, i.e. organoleptic, homogeneity, pH, dispersion, and viscosity tests on all three formulas (F1, F2, and F3), met the requirements. The results of the one-way ANOVA analysis revealed a significant difference in the experimental group with a score of 0.022 (p < 0.05). Hence, the most effective formula for curing burns was F3, with a 1.5% extract concentration and a healing percentage of 19.175%.
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