Antidiabetic drug profile of COVID-19 patients with comorbid diabetes mellitus

Authors

  • Didik Hasmono Universitas Airlangga, Surabaya, East Java, Indonesia
  • Samirah Samirah Universitas Airlangga, Surabaya, East Java, Indonesia https://orcid.org/0000-0002-1308-5803
  • Ni Putu Ayu Deviana Gayatri Universitas Airlangga, Surabaya, East Java, Indonesia
  • Naning Ni’mawati Universitas Airlangga, Surabaya, East Java, Indonesia https://orcid.org/0009-0008-5229-6444
  • Halim Prihayau Jaya Dr. Soetomo Hospital, Surabaya, East Java, Indonesia
  • Erwin Astha Triono Universitas Airlangga, Surabaya, East Java, Indonesia

DOI:

https://doi.org/10.46542/pe.2023.234.168172

Keywords:

Antidiabetic, COVID-19, Diabetes, Drug profile

Abstract

Background:  Diabetes mellitus (DM) is a risk factor that can increase the severity and mortality of patients with COVID-19 infection. The use of antidiabetic drugs for diabetes mellitus patients with COVID-19 infection is very important to reduce these impacts.

Objective: This study aimed to determine the antidiabetic drug profiles of COVID-19 patients with comorbid diabetes mellitus.     

Method: This study was an analytic cross-sectional electronic medical record data of patients diagnosed with COVID-19 and comorbid Diabetes Mellitus. It was carried out from May until December 2020.     

Result: A total of 106 patients were involved and different types of antidiabetic drugs were used i.e., glimepiride in 32 patients (31.13%), metformin in 18 patients (16.98%), combination of long-acting and rapid-acting insulin in 20 patients (18.87%), and combination of metformin and glimepiride in 18 patients (16.98%).    

Conclusion: The most commonly prescribed single antidiabetic therapy in patients with COVID-19 and comorbid diabetes mellitus was glimepiride, followed by glimepiride and metformin. The most common insulin therapy combination was long-acting and rapid-acting insulin.

Author Biographies

Didik Hasmono, Universitas Airlangga, Surabaya, East Java, Indonesia

Department of Pharmacy Practice, Faculty of Pharmacy

Samirah Samirah, Universitas Airlangga, Surabaya, East Java, Indonesia

Department of Pharmacy Practice, Faculty of Pharmacy

Ni Putu Ayu Deviana Gayatri, Universitas Airlangga, Surabaya, East Java, Indonesia

Department of Pharmacy Practice, Faculty of Pharmacy

Naning Ni’mawati, Universitas Airlangga, Surabaya, East Java, Indonesia

Faculty of Pharmacy

Halim Prihayau Jaya, Dr. Soetomo Hospital, Surabaya, East Java, Indonesia

Pharmacy Installation

Erwin Astha Triono, Universitas Airlangga, Surabaya, East Java, Indonesia

Internal Medicine Department, Faculty of Medicine

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Published

10-10-2023

How to Cite

Hasmono, D., Samirah, S., Gayatri, N. P. A. D., Ni’mawati, N., Jaya, H. P., & Triono, E. A. (2023). Antidiabetic drug profile of COVID-19 patients with comorbid diabetes mellitus. Pharmacy Education, 23(4), p. 168–172. https://doi.org/10.46542/pe.2023.234.168172

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