Application of ATC/DDD methodology to analyse antibiotic consumption in internal medicine department: A review
DOI:
https://doi.org/10.46542/pe.2023.234.251258Keywords:
Antibiotic, ATC/DDD, Consumption, Defined Daily Dose, Internal medicineAbstract
Background: Antibiotic resistance has become a significant problem due to its impact such as higher medical costs, prolonged hospital stays, and increased mortality. The Internal Medicine Ward has a high consumption of antibiotics, particularly for gastroenteritis, typhoid, diabetic ulcer, urinary tract infection, and sepsis. The DDD/ATC systems applied in hospitals may provide valid data to evaluate antimicrobial usage as a global standard method.
Objective: To explore the antibiotic use pattern in the internal medicine department based on the DDD/ATC system.
Method: The authors explored articles from the database in PMC, Research Gate, and Google Scholar from July 11st, 2020, to July 21st, 2020. The authors included original articles/research, case reports, and meta-analyses from 2006 to 2020, which discussed DDD/100 patient-days or DDD/100 bed-days antibiotics in the internal medicine ward. A major criterion was to ensure all subjects in publications were adults aged above 18.
Result: Penicillin is the most consumed (127.9 DDD/100 bed-days), followed by Cephalosporin (41.42 DDD/100-bed-days) and Fluoroquinolone (25.87 DDD/100 bed-days).
Conclusion: The most widespread antibiotic use in Internal Medicine in many countries showed an improvement in rational antibiotic consumption.
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