Exploration of probiotics on antioxidant activity of serum NLC coenzyme Q10 using the DPPH (2,2-diphenyl-1-picrylhidrazyl) method
DOI:
https://doi.org/10.46542/pe.2024.242.140144Keywords:
Antiaging, Coenzyme Q10, DPPH, NLC, ProbioticAbstract
Background: The skin ageing process can be slowed by routinely caring for the skin using serum cosmetics containing antioxidants such as Co-enzyme Q10 (CoQ10). However, CoQ10 has a drawback, which is low penetration into the skin. In this study, an antiaging serum preparation with the active ingredient NLC-CoQ10 was prepared. Probiotics were added to this preparation as a second active ingredient to enhance antioxidant activity.
Objective: This study aimed to analyse the effect of probiotic concentration on the physical characteristics and antioxidant activity of NLC-CoQ10 serum.
Method: NLC-CoQ10 was mixed with serum base and 0% probiotic (Formula One), 2% probiotic (Formula Two), and 4% probiotic (Formula Three). After that, physical characteristics and antioxidant activity were observed.
Results: The results show that the physical characteristics of all formulas fulfil the specifications. All formulas had pH values between 4 and 7 and a viscosity value between 230 and 1150 cPs. The formula with the highest viscosity value is F1, 352.00 ± 2.00. All formulas have statistically different IC50 values. IC50 values for F1, F2 and F3 respectively, are 317.809 ± 2.117; 307.985 ± 2.089; 257.549 ± 1.573.
Conclusion: The antioxidant activity increases with increasing concentrations of probiotics in NLC-CoQ10 serum. Meanwhile, the viscosity value decreases with a decreasing concentration of probiotics.
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