Identification of Δ9-tetrahydrocannabinol compounds in Cannabis sativa using gas chromatography-mass spectrometry

Authors

  • Gilang Bhakti Nusantara Faculty of Military Pharmacy, Republic of Indonesia Defense University, Bogor, Indonesia
  • Tesia Rahmania Faculty of Military Pharmacy, Republic of Indonesia Defense University, Bogor, Indonesia

DOI:

https://doi.org/10.46542/pe.2024.246.4349

Keywords:

Cannabis sativa, Duquenois, GC-MS, Narcotic, Narcotic abuse

Abstract

Background: Narcotics are divided into three types natural, semisynthetic and synthetic. Cannabis is included in the Cannabaceae family with the species Cannabis sativa L. This plant is known as a plant that has psychotropic effects because it contains the main alkaloids cannabinol, cannabidiol, and Δ9-Tetrahydrocannabinol.

Objective: This study aims to identify the presence of Δ9-Tetrahydrocannabinol in samples.

Method: The method used is the Duquenois colour test, Fast Blue, Gas Chromatography-Mass Spectrometry (GC-MS) confirmation.

Result: The result shows that Dequenoise test positive giving a blue color and Fast Blue color test positive giving a brick red. The GC-MS analysis shows the presence of Δ9-Tetrahidrocannabivarin,  Cannabichrome, Dronabinol, Cannabigerol, and Cannabinol. The chromatogram revealed five peaks, with the main compound identified as dronabinol.

Conclusion: Five compounds found in sample were 9-tetrahydrocannabivarin, cannabichromene, dronabinol, cannabigerol, and cannabinol, which were positive for marijuana.

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Published

14-06-2024

How to Cite

Nusantara, G. B., & Rahmania, T. (2024). Identification of Δ9-tetrahydrocannabinol compounds in Cannabis sativa using gas chromatography-mass spectrometry. Pharmacy Education, 24(6), p. 43–49. https://doi.org/10.46542/pe.2024.246.4349