Drug utilisation study of parenteral nutrition in neonate patients

Authors

  • Arina Dery Puspitasari Department of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Indonesia & Doctoral Programme in Pharmaceutical Science, Faculty of Pharmacy, Universitas Airlangga, Indonesia & Universitas Airlangga Hospital, Indonesia https://orcid.org/0000-0002-5641-0370
  • Satya Andiva Bachelor Programme Study of Pharmacy, Faculty of Pharmacy, Universitas Airlangga, Indonesia
  • Hargus Haraudi Barkah Universitas Airlangga Hospital, Indonesia
  • Mahendra Tri Arif Sampurna Universitas Airlangga Hospital, Indonesia & Department of Pediatric, Faculty of Medicine, Universitas Airlangga, Indonesia
  • Budi Suprapti Department of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Indonesia & Universitas Airlangga Hospital, Indonesia https://orcid.org/0000-0001-9060-8041
  • Mariah Ulfa Universitas Airlangga Hospital, Indonesia
  • Diah Sukmawati Pangarsih Universitas Airlangga Hospital, Indonesia
  • Widia Yuniarti Universitas Airlangga Hospital, Indonesia

DOI:

https://doi.org/10.46542/pe.2024.243.310314

Keywords:

Calorie intake, Low birth weight, Neonatal intensive care, Neonatal mortality, Osmolarity, Parenteral nutrition

Abstract

Background: The neonatal period is an individual adaptation with a higher risk of death and complications. Using parenteral nutrition to meet nutritional imbalances in neonates requires close supervision to prevent complications caused by inappropriate administration.

Objective: This study aims to examine the effectiveness of parenteral nutrition (PN) in weight changes, patient caloric balance, osmolarity, and side effects.

Methods: This study used a prospective observation method and was carried out from April to June 2023 at Universitas Airlangga Hospital. Data were obtained through medical records and direct observation of the patient’s condition after the patient’s parents signed an informed consent. Data analysis was carried out descriptively.

Results: PN was given centrally or peripherally to 71 patients. Of those, 21 were low birth weight patients. Caloric balance was achieved in almost all patients. All patients gained weight, although only 20.89% experienced a return to birth weight. Phlebitis occurred in 35.22% of patients.

Conclusion: Parenteral nutrition is efficacious in increasing the patient’s weight, depending on the suitability of the calculation between calories needed and calories obtained and the osmolarity of the preparation.

References

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Published

13-05-2024

How to Cite

Puspitasari, A. D., Andiva, S., Barkah, H. H., Sampurna, M. T. A., Suprapti, B., Ulfa, M., Pangarsih, D. S., & Yuniarti, W. (2024). Drug utilisation study of parenteral nutrition in neonate patients. Pharmacy Education, 24(3), p. 310–314. https://doi.org/10.46542/pe.2024.243.310314