Utilisation study of antipyretic drugs in paediatric patients
DOI:
https://doi.org/10.46542/pe.2024.243.234239Keywords:
Antipyretic, Fever, Medicine, Metamizole, Paediatric, ParacetamolAbstract
Background: Fevers are common in children with underlying diseases, so antipyretics are often used. However, no specific guidelines exist for the use of antipyretics in children.
Objective: This study aimed to determine the profile of antipyretics used by paediatric inpatients at Universitas Airlangga Hospital and to identify possible side effects and interactions associated with antipyretics use.
Method: This observational study was conducted from March to June 2023. Convenience sampling was used to collect retrospective data from patients’ medical records, which were then analysed descriptively.
Result: A total of 87 paediatric patients met the inclusion criteria. All paediatric patients received intravenous metamizole as an antipyretic treatment (100.0%), with 3 x 8 - 20 mg/kgBW as needed (55.2%) being the most used dosage regimen. Metamizole as monotherapy was the most widely used pattern (80.5%), and it showed the shortest mean duration of therapy. Paracetamol was only used in switching (11.5%) and alternating (8.1%) patterns. Abdominal pain was the most actual suspected side effect of metamizole (3.4%). No potential drug interactions associated with antipyretics were found.
Conclusion: In general, intravenous metamizole effectively reduced fever in most paediatric patients at Universitas Airlangga Hospital.
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