ICOPMAP SPECIAL EDITION Lactic acid clay mask formulation with plasticiser variations
DOI:
https://doi.org/10.46542/pe.2025.252.1521Keywords:
Clay mask, Glycerol, Lactic acid, Physical stability, SorbitolAbstract
Background: Lactic acid can inhibit the growth of acne-causing bacteria, moisturise, and remove dead skin cells. It can be formulated in clay mask preparations. One of the components of a clay mask is a plasticiser, which increases stability and controls the drying of preparations.
Objective: To compare the effect of sorbitol and glycerol as plasticisers on the physical stability of lactic acid clay masks.
Method: Clay masks were made with plasticiser concentrations of 0%, 2%, 3%, 4%, and 5%, then evaluated (organoleptic, homogeneity, pH, spreadability, viscosity, and flow properties) for three weeks. Furthermore, statistical analysis was done using two-way ANOVA and Friedman on the evaluation results with a p-value < 0.05.
Result: Lactic acid clay mask with sorbitol had a range of pH values of 4.68–5.46, spreadability of 2.97–3.78 cm, drying speed of 10.92–15.08 minutes, and viscosity of 110.73–292.71 cps. In comparison, masks with glycerol had a pH value range of 4.64–5.54, spreadability of 2.67–3.73 cm, drying speed of 10.57–14.67 minutes, and viscosity of 107.417–282.55 cps.
Conclusion: Sorbitol and glycerol had the same effectiveness as a plasticiser in increasing the physical stability of lactic acid clay mask preparations.
References
Ahmad, F. J., Ali, J., Iqubal, M. K., & Narang, J. K. (2017). Pharmaceutical Sciences Cosmetics. New Delhi: Pathshala.
Bruning, E., Chen, Y., McCue, K. A., Rubino, J. E., & Brown, A. D. G. (2020). A 28-day clinical assessment of a lactic acid-containing antimicrobial intimate gel wash formulation on skin tolerance and impact on the vulvar microbiome. Antibiotics, 9, 55. https://doi:10.3390/antibiotics9020055
Chen, M. J., Liu, J. R., Sheu, J. F., Lin, C. W., & Chuang, C. L. (2006). Study on skin care properties of milk kefir whey. Asian-Australian Journal of Animal Science, 6(19), 905‒908. https://doi.org/10.5713/ajas.2006.905
Cheng, L. H., Karim, A. A., & Seow, C. C. (2006). Effects of water–glycerol and water–sorbitol interactions on the physical properties of konjac glucomannan films. Journal of Food Science, 71, E62‒E67. https://doi.org/10.1111/j.1365-2621.2006.tb08898.x
El Enshasy, H. A., Ramzi, A. A. A., Azzam, A., Nor, Z. O., Roslinda, A. M., Ong, M. L., & Ramlan, A. (2015). Lactic acid applications in pharmaceutical and cosmeceutical industries. Journal of Chemical and Pharmaceutical Research, 7(10),729‒735.
Elmitra. (2017). Dasar-dasar farmasetika dan sediaan semi solid. Yogyakarta: Deepublish.
Esmaeili, M., Gholamreza, P., & Reza, B. (2017). Optimising the mechanical and physical properties of thermoplastic starch via tuning the molecular microstructure through co-plasticization by sorbitol and glycerol. Polym Int, 66, 809–819. https://www.doi.org/10.1002/pi.5319
Hazrol, M. D., Sapuan, S. M., Zainudin, E. S., Zuhri, M. Y. M., & Abdul Wahab, N. I. (2021). Corn starch (Zea mays) Biopolymer plastic reaction in combination with sorbitol and glycerol. Polymers, 13, 242. https://doi.org/10.3390/polym13020242
Hidayati, S., Ahmad, S. Z., & Astri, A. (2015). Application of sorbitol in the production of biodegradable films from nata de cassava. Reactor, 15(3), 196‒204. https://doi.org/10.14710/reaktor.15.3.195-203
Hidayati, N., Ivan, N., & Saifudin, Z. (2019). Optimization of the formula of ethanol extract syrup of breadfruit leaves (Artocarpus altilis) with sorbitol sweetener and propylene glycol co-solvent. CERATA Jurnal Ilmu Farmasi, 10(2), 67‒76. https://doi.org/10.61902/cerata.v10i2.80
Luthfiyana, N., Nurhikma, N., & Hidayat, T. (2019). Characteristics of peel off gel mask from seaweed (Eucheuma cottonii) porridge. Jurnal Pengolahan Hasil Perikanan Indonesia, 22(1), 119. https://doi.org/10.17844/jphpi.v22i1.25888
Mardikasari, S. A., Mallarangeng, A. N. T. A., & Juswita, W. S. Z. E. (2017). Formulation and stability test of lotion from ethanol extract of guava leaves (Psidium guajava L.) as an antioxidant. Jurnal Farmasi, Sains dan Kesehatan; 3(2), 28‒32. http://dx.doi.org/10.33772/pharmauho.v3i2.3542
Nisa, O. N. L., Hermadi, A. V. L., Khoiriyah, H., Purwojati, N., & Ashari, N. (2017). Stability test on banana leaf extract gel (Gelek Usang). Proceeding 6th University Research Colloquium: Seri Pengabdian Kepada Masyarakat: 223-‒227.
Putra, M. M., Dewantara, I. G. N. A., & Swastini, D. A. (2014). The effect of storage time on the pH value of cold cream preparations combining mangosteen peel extract, pegagan herb and agarwood leaves. Jurnal Farmasi Udayana, 3(1), 18‒21.
Riyanto, D. N., Adrianus, R. U., & Setijawati, E. (2017). The effect of adding sorbitol on the physicochemical characteristics of edible films made from wheat starch. Jurnal Teknologi Pangan Dan Gizi, 16(1), 14‒20. https://www.doi.org/10.33508/jtpg.v16i1.1386
Rowe, R., Sheskey, P., & Quinn, M. (2009). Handbook of pharmaceutical exipients. Ed. 6th. Pharmaceutical Press. London.
Santoso, C. C., Darsono, F. L., & Hermanu, L. S. (2018). Formulation of a facial mask preparation made from pumpkin extract (Cucurbita moschata) in clay form using bentonite and kaolin as clay minerals. Journal of Pharmacy Science and Practice, 5(1), 64–69. https://doi.org/10.33508/jfst.v5i2.2138
Sanyang, M. L., Sapuan, S. M., Jawaid, M., Ishak, M. R., & Sahari, J. (2016). Effect of plasticiser type and concentration on physical properties of biodegradable films based on sugar palm (Arenga pinnata) starch for food packaging. Journal of food science and technology, 53(1), 326–336. https://doi.org/10.1007/s13197-015-2009-7
Setiarto R. H. B. (2020). Teknologi pengemasan pangan antimikroba yang ramah lingkungan. Depok: Guepedia.
Septiani, S., Wathoni, N., & Mita, S. (2011). Formulation of antioxidant gel mask preparation from ethanol extract of belinjo seeds. Fakultas Farmasi Universitas Padjajaran, Bandung.
Silvia, B. M., & Dewi, M. L. (2022). Literature study of the influence of type and concentration of base on the characteristics of peel-off gel masks. Jurnal Riset Farmasi, 2(1), 31‒40. https://doi.org/10.29313/jrf.v2i1.702
Sinko PJ. (2022). Martin’s physical pharmacy and pharmaceutical sciences (7th Ed). Philadelphia: Wolters Kluwer.
Sukmawati, N. M. A., Arisanti, C. I. S., & Wijayanti, N. P. A. D. (2014). The effect of variations in the concentration of PVA, HPMC, and glycerin on the physical properties of a peel-off gel facial mask made from 96% ethanol extract of mangosteen peel (Garcinia mangostana L.). Jurnal Farmasi Udayana, 2(3), 35–42.
Usuki, A., Ohashi, A., Sato, H., Ochiai, C., Ichihashi, M., & Funasaka, Y. (2003). The inhibitory effect of glycolic acid and lactic acid on melanin synthesis in melanoma cells. Exp Dermatol, 12(2), 43‒50.
Utari, K. D. P., Unique, I. G. A. N. P., Aryani, N. W. G., Arisanti, C. I. S., & Samirana, P. O. (2019). Optimization of cetyl alcohol concentration as a thickening agent in turmeric rhizome extract cream formula (Curcuma omestica). Jurnal Farmasi Udayana, 7(2), 40‒44. https://doi.org/10.24843/JFU.2018.v07.i02.p01
Wiyono, A. S., & Mustofani, D. (2019). The effectiveness of the crude extract gel of pineapple skin bromelain (Ananus comosus L. Merr) as a result of formula optimization on mice that were given bruises. Jurnal Ilmiah As-Syifaa, 11(2), 112–123. https://doi.org/10.33096/jifa.v11i2.569
Wypych, G. (2017). Handbook of plasticisers. Edisi Ketiga. ChemTec Publishing, Canada.
Yulianti, E., & Binardjo, A. (2010). The effect of rice flour particle size on the dead skin cell lifting power of cold powder scrub. Fakultas Farmasi Univesitas Ahmad Dahlan, Yogyakarta.
