Drug related problems in patients with pneumonia at Jasa Kartini Tasikmalaya city hospital
DOI:
https://doi.org/10.46542/pe.2023.232.7177Keywords:
Drug related problems (DRPs), PneumoniaAbstract
Background: Pneumonia is a severe infection that attacks lung tissue and is caused by bacteria, viruses or fungi. The incidence of Drug Related Problems (DRPs) in pneumonia can affect treatment outcomes leading to increased mortality and morbidity.
Objective: To determine DRPs in pneumonia patients hospitalised at the Jasa Kartini Hospital (RSJK) Tasikmalaya City.
Method: A descriptive observational study with retrospective data collection and consecutive sampling was conducted from January - December 2021. Demographic, quantitative, and DRPs data analysis with the number of patients who met the inclusion criteria (n = 69).
Result: Based on demographics, pneumonia mostly affects elderly patients (> 65 years) by 29.0%, female (52.2%), housewife work (34.8%) with Length Of Stay between five and six days (42.0%), diagnosis of pneumonia with comorbidities (73.9%), as well as payment status using private payment (43.5%). Based on quantitative analysis, the most widely used drugs were non-generic drugs (70.1%) and antibiotics (18.2%). Drug Related Problems (DRPs) as many as 50 cases with an category indication without drugs 11 cases (22.0%) which include indications of pulmonary tuberculosis, diarrhea, and hypertension; drugs without indication 0 cases; underdose in eight cases (16.0%) which included Analsik, Largactil, Alganax, Sanmol, Ketorolac, Risperidon, ranitidine; drug overdose in 12 cases (24.0%) which included Tracetat, Sanmol Syrup, Codipront, Citicolin, Lansoprazole, Lancid, Furosemid; wrong drug 0 cases, drug interaction 19 cases (38.0%) with major (10.5%), moderate (68.4%) and minor (21.1%) categories; and adverse drugs 0 cases.
Conclusion: Several treatments for pneumonia patients at the Tasikmalaya City Hospital for the period January to December 2021 experienced DRPs.
References
Anonim. (2018). Hasil Riset Kesehatan Dasar Tahun 2018. Kementrian Kesehatan RI, 53(9), 1689–1699
Azmi, S., Aljunid, S. M., Maimaiti, N., Ali, A. A., Muhammad Nur, A., De Rosas-Valera, M., Encluna, J., Mohamed, R., Wibowo, B., Komaryani, K., & Roberts, C. (2016). Assessing The Burden Of Pneumonia Using Administrative Data From Malaysia, Indonesia, And The Philippines. International Journal of Infectious Diseases, 49, 87–93. https://doi.org/10.1016/j.ijid.2016.05.021
Garin, N., Sole, N., Lucas, B., Matas, L., Moras, D., Rodrigo-Troyano, A., Gras-Martin, L., & Fonts, N. (2021). Drug related problems in clinical practice: a cross-sectional study on their prevalence, risk factors and associated pharmaceutical interventions. Scientific Reports, 11(1), 1–11. https://doi.org/10.1038/s41598-020-80560-2
Hendera, & Rahayu, S. (2018). Interaksi Antar Obat pada Peresepan Pasien Rawat Inap Pediatrik Rumah Sakit X dengan Menggunakan Aplikasi Medscape. Journal of Current Pharmaceutical Sciences, 1(2), 75–80
Ivanova, N., Gugleva, V., Dobreva, M., Pehlivanov, I., Stefanov, S., & Andonova, V. (2016). Pneumonia: Drug-Related Problems and Hospital Readmissions. Intech, 1(tourism), 13. https://doi.org/http://dx.doi.org/10.5772/intechopen.100127
Jain, S., Self, W. H., Wunderink, R. G., Fakhran, S., Balk, R., Bramley, A. M., Reed, C., Grijalva, C. G., Anderson, E. J., Courtney, D. M., Chappell, J. D., Qi, C., Hart, E. M., Carroll, F., Trabue, C., Donnelly, H. K., Williams, D. J., Zhu, Y., Arnold, S. R., Ampofo, K., Waterer, G.W., Levine, M., Lindstrom, S., Winchell, J.M., Katz, J.M., Erdman, D., Schneider, E., Hicks, L.A., McCullers, J.A., Pavia, A.T., Edwards, K.M., & Finelli, L. (2015). Community-Acquired Pneumonia Requiring Hospitalization among U.S. Adults. New England Journal of Medicine, 373(5), 415–427. https://doi.org/10.1056/nejmoa1500245
Kemenkes RI. (2009). Menteri Kesehatan Republik Indonesia Nomor 364/MENKES/SK/V/2009 Tentang Pedoman Penanggulangan Tuberkulosis (TB). Kementerian Kesehatan Republik Indonesia. https://doi.org/10.1038/132817a0
Kemenkes RI. (2011). Situasi diare di Indonesia. Jurnal Buletin Jendela Data & Informasi Kesehatan, 2, 1–44
Kemenkes RI. (2020). Health Statistics (Health Information System). In B. Hardhana, F. Sibuea, & W. Widiantini (Eds.), Short Textbook of Preventive and Social Medicine. Kementerian Kesehatan Republik Indonesia. https://doi.org/10.5005/jp/books/11257_5
Kowalak, J.P. (2011). Buku Ajar Patofisiologi. Jakarta : EGC
Martono, H. (2011). Aspek fisiologik dan patologik akibat proses menua. Jakarta : Balai Penerbit Fakultas Kedokteran Universitas Indonesia
Nuryanti. (2017). Bahan Ajar Rekam Medis dan Informasi Kesehatan (RMIK) Farmakologi (p. 266). Kementerian Kesehatan Republik Indonesia
PCNE. (2020). Classification for Drug related problems V9.1. Word Journal Of The International Linguistic Association, 9.1.Available from: http://www.pcne.org/upload/files/15_PCNE_classification_V4-00.pdf
PDPI. (2014). Pneumonia komunitas : Pedoman Diagnosis dan Penatalaksanaan Di Indonesia (2nd ed.). Badan Penerbit FKUI
Unger, T., Borghi, C., Charchar, F., Khan, N. A., Poulter, N. R., Prabhakaran, D., Ramirez, A., Schlaich, M., Stergiou, G. S., Tomaszewski, M., Wainford, R. D., Williams, B., & Schutte, A. E. (2020). 2020 International Society of Hypertension Global Hypertension Practice Guidelines. Hypertension, 75(6), 1334–1357. https://doi.org/10.1161/HYPERTENSIONAHA.120.15026
Viegi, G., Pistelli, R., Cazzola, M., Falcone, F., Cerveri, I., Rossi, A., & Ugo Di Maria, G. (2006). Epidemiological survey on incidence and treatment of community acquired pneumonia in Italy. Respiratory Medicine, 100(1), 46–55. https://doi.org/10.1016/j.rmed.2005.04.013
Vila-Corcoles, A., Ochoa-Gondar, O., Rodriguez-Blanco, T., Raga-Luria, X., & Gomez-Bertomeu, F. (2009). Epidemiology of community-acquired pneumonia in older adults: A population-based study. Respiratory Medicine, 103(2), 309–316. https://doi.org/10.1016/j.rmed.2008.08.006
