Exploring academic performance of undergraduate students offering Pharmacology course in a Nigerian university: A cross-sectional observational study

Authors

  • Ogochukwu Ngozi Nwaefulu Department of Pharmacology and Toxicology, Faculty of Pharmacy, Madonna University, Rivers State, Nigeria
  • Wilson Inalegwu Akpakwu Department of Pharmacology and Toxicology, Faculty of Pharmacy, Madonna University, Rivers State, Nigeria
  • Blessing Akporotu Department of Pharmacology and Toxicology, Faculty of Pharmacy, Delta State University, Abraka, Delta State, Nigeria
  • Grace James Udoyen Institute for Advanced Studies, Obafemi Awolowo University, Ile Ife, Osun State, Nigeria

DOI:

https://doi.org/10.46542/pe.2026.261.171182

Keywords:

Academic performance, Challenge, Coping strategy, Pharmacology

Abstract

Background: Pharmacology students often struggle with academic performance due to the subject’s complexity, reliance on rote memorisation, and limited practical exposure. The study’s objective is to evaluate factors influencing student performance, identify challenges, propose improvement strategies, and compare outcomes in Pharmacology versus Pharmaceutical Microbiology.   

Methods: A cross-sectional study was conducted among students of Pharmacology and Pharmaceutical Microbiology at Madonna University, Nigeria (July–December 2024). Stratified random sampling ensured proportional representation by year and department. Data were collected via questionnaires, focus groups, and interviews. Quantitative data were analysed with SPSS 23, while qualitative data underwent thematic analysis. Findings were triangulated to enhance validity.

Results: Pharmacology was consistently perceived as abstract, bulky, and poorly taught, with most students reporting unsatisfactory performance. Pharmaceutical Microbiology was clearer and more engaging, though practical skills remained weak. Regression analysis confirmed course enrollment as a significant predictor of exam performance, while socioeconomic factors were not.

Conclusion: Student outcomes are shaped by curriculum design and instructional quality. Pharmacology is hindered by content overload and lack of application, whereas Pharmaceutical Microbiology benefits from clarity but requires stronger laboratory training.

References

Agaga, L. A., & John, T. A. (2016). Conception of pharmacological knowledge and needs amongst Nigerian medical students at Lagos State University College of Medicine: Implication for future biomedical science in Africa. Nigerian Journal of Physiological Sciences, 31, 083–091

Alsanosi, S. M. (2022). A new vision of teaching clinical pharmacology and therapeutics for undergraduate medical students. Advances in Medical Education and Practice, 13, 567–575. https://doi.org/10.2147/AMEP.S359704)

Becker, K., & Park, K-S. (2011). Effects of integrative approaches among science, technology, engineering, and mathematics (STEM) subjects on students’ learning: A preliminary meta-analysis. Journal of STEM Education, 12(5 & 6), 23–37. https://jstem.org/jstem/index.php/JSTEM/article/download/1509/1394

Braun, V., & Clarke, V. (2006). Using thematic analysis in psychology. Qualitative Research in Psychology, 3(2), 77–101. https://doi.org/10.1191/1478088706qp063oa

Broer, M., Bai, Y., & Fonseca, F. (2019). Socioeconomic inequality and educational outcomes: Evidence from twenty years of TIMSS. Springer Cham, 5,72. https://doi.org/10.1007/978-3-030-11991-1

Brown, E. F., & White, G. H. (2019). Factors influencing the academic performance of students in pharmacology courses: A systematic review. Journal of Medical Education, 47(2), 7892.

Brown, M., Smith, L., & Taylor, J. (2022). A systematic review of student performance in pharmacology courses worldwide: Trends and challenges. Pharmacy Education, 22(1), 15–24. https://doi.org/10.46542/pe.2022.221.1524

Chisholm-Burns, M. A., Spivey, C. A., Sherwin, E., Williams, J., & Phelps, S. (2019). Development of an instrument to measure academic resilience among pharmacy students. American Journal of Pharmaceutical Education, 83(6), 6896. https://doi.org/10.5688/ajpe6896.

Cochran, W.G. (1977). Sampling techniques (3rd ed.). John Wiley & Sons.

Cortina, J. M. (1993). What is coefficient alpha? An examination of theory and applications. Journal of Applied Psychology, 78(1), 98–104. https://doi.org/10.1037/0021-9010.78.1.98

Eukel, H. N., Frenzel, J. E., & Cernusca, D. (2017). Educational gaming for pharmacy students– design and evaluation of a diabetes-themed escape room. American Journal of Pharmaceutical Education, 81(7), 6265. https://doi.org/10.5688/ajpe8176265

Fasinu, P. S., & Wilborn, T. W. (2024). Pharmacology education in the medical curriculum: Challenges and opportunities for improvement. Pharmacology Research & Perspectives, 12(1), e1178. https://doi.org/10.1002/prp2.1178

Fokkens-Bruinsma, M., Sluijsmans, D., Segers, M., & Jansen, E. (2021). First-year academic achievement: The role of academic self-efficacy, self-regulated learning and beyond classroom engagement. Assessment & Evaluation in Higher Education, 46(7), 1115–1126. https://doi.org/10.1080/02602938.2020.1822286

Gill, M., Andersen, E., & Hilsmann, N. (2019). Best practices for teaching pharmacology to undergraduate nursing students: A systematic review of the literature. Nurse Education Today, 74, 15-24. https://doi.org/10.1016/j.nedt.2018.11.017

Guilding, C., Kelly-Laubscher, R., Netere, A., Babey, A. M., Restini, C., Cunningham, M., Kelly, J. P., Koenig, J., Karpa, K., Hawes, M., Tucker, S. J., Angelo, T. A., & White, P. J. (2023). Developing an international concept-based curriculum for pharmacology education: The promise of core concepts and concept inventories. British Journal of Clinical Pharmacology, 9(2), 1–16. https://doi.org/10.1111/bcp.15985.

Ibrahim, M. A., Adedoyin, R. A., & Ojo, O. (2018). Factors influencing students’ performance in pharmacology: A study in Nigeria. BMC Medical Education, 18(1), 34. https://doi.org/10.1186/s12909-018-1141-5.

Jegede, A. O., Olabanji, K. T., & Arolagbade, T. (2024). Exploring studentperceptions: Factors influencing academic performance in a school of pharmacy in Nigeria. Pharmacy Education, 24(1), 238–247. https://doi.org/10.46542/pe.2024.241.238247

Khilnani, G. (2014). Need for restructuring practical pharmacology undergraduate curriculum. National Journal of Physiology, Pharmacy and Pharmacology, 4, 1–3. https://doi.org/10.5455/njppp.2014.4.010120141.

Kolb, D. A. (2014). Experiential learning: Experience as the source of learning and development. FT Press.

Mengesha, A. K., Beyna, A. T., Chanie, G. S., Taye, W. A., Alemayehu, T. T., Bizuneh, G. K., Aragie, Y. S., Geremew, G. W., & Ayele, H. S. (2025). Impact of pharmacology perception and learning strategies on academic achievement in undergraduate pharmacy students. Scientific Reports, 15, 16425. https://doi.org/10.1038/s41598-025-91510-1

Morgan, J. H. C. (2003). New approaches to training general practitioners. Postgraduate Medical Journal, 79, 187–188. https://doi.org/10.1136/pmj.79.930.187

Murphy, J. E., Formea, C. M., & Fullerton, L. (2017). Implementation and evaluation of a preAPPE simulation-based training program in preparation for an acute care advanced pharmacy practice experience. Currents in Pharmacy Teaching and Learning, 9(4), 688693.

Ogunleye, O. O., Oguntokun, O. J., Fashola, A., & Adebayo, A. (2022). Survey of opinions of medical students on pharmacology Eeducation in a Nigerian medical school. International Journal of Sciences: Basic and Applied Research (IJSBAR), 63(1), 197–207. https://www.gssrr.org/JournalOfBasicAndApplied/article/view/14377

Sharma, R., Verma, U., Kapoor, B., & Chopra, V. S. (2004). Novel teaching approaches in pharmacology. JK Science, 6(3), 172–173. http://jkscience.org/archive/volume63/novel.pdf

Sharma, S. (2004). Applied multivariate techniques. John Wiley & Sons.

Streiner, D. L. (2003). Starting at the beginning: An introduction to coefficient alpha and internal consistency. Journal of Personality Assessment, 80, 99–103. https://doi.org/10.1207/S15327752JPA8001_18

Uma, A. B., Yegnanarayan, R., & Yadav, G. E. (2013). Attitude, perception and feedback of second year medical students on teaching–learning methodology and evaluation methods in pharmacology: A questionnaire based study. Nigerian Medical Journal, 34(1), 33–39. https://doi.org/10.4103/0300-1652.108891

Wolters, C.A., & Brady, A.C. (2021). College students’ time management: A self-regulated learning perspective. Educational Psychology Review, 33, 1319–1351. https://doi.org/10.1007/s10648-020-09519-z.

Yamane, T. (1967). Statistics: An introductory analysis. Harper and Row, New York.

Downloads

Published

16-03-2026

How to Cite

Nwaefulu , O. N., Akpakwu , W. I., Akporotu, B., & Udoyen, G. J. (2026). Exploring academic performance of undergraduate students offering Pharmacology course in a Nigerian university: A cross-sectional observational study. Pharmacy Education, 26(1), p. 171–182. https://doi.org/10.46542/pe.2026.261.171182

Issue

Section

Research Article